Interactions with Grapefruit..

Name: Grapefruit

Scientific Name: Citrus Paradisi

Family: Rutaceae

Internal Pulp colour: White, red or pink. The pink and red types are high in beta carotene.

Drug Interations:

Grapefruit causes serious interactions with many commonly prescribed medications.

Grapefruit contains the flavanone naringin alongside the two furanocoumarins bergamottin and dhydroxybergamottin , which inhibit the cytochrome P450 3A4 isoenzyme in the intestinal wall, thus preventing the pre-systemic "first-pass" oxidative metabolism for a wide variety of drugs. When the action of this enzyme is inhibited, the drugs' bio-availabilities increase, more of the drugs may be absorbed and hence increasing the drug effects. Increased drug effects may then lead to side effects or adverse  reactions or toxicity.. . 

Whether you will experience a drug interaction depends on  few factors, including individual genetics, the type of medication, the dosage and the amount of grapefruit consumed. Please consult your doctor or pharmacist for more information.